NS
NeuroSync ERP
User Manual v4.2 · NS-UM-2026-v4.2 · IS360 Technologies & Services Pvt. Ltd.
✓ CDSCO TEST LICENSE GRANTED
SaMD CLASS B
Chapter 1 · neurosync-erp.com/portal · index.html

Account Registration & Login

Before you begin

NeuroSync ERP™ runs entirely in your browser at neurosync-erp.com/portal.html. No app installation required. Your session is encrypted (AES-256) and governed by HIPAA & India's DPDP Act 2023. All EEG data stays within AWS ap-south-1 (Mumbai) on a PostgreSQL backend.

New Account — Step by Step

1
Navigate to the portal. Open neurosync-erp.com/portal.html in Chrome, Edge, or Safari (desktop preferred). The login modal appears automatically.
2
Click "Create account →". Below the Sign In button. The Registration panel slides in with five sections: Personal Details, Professional Details, Subscription Plan, Voucher, and Credentials.
3
— or — Sign up with Google. Tap Continue with Google on the login screen. A Google account picker appears. Selecting an existing Google account auto-fills your name, email, and profile picture. If this is your first visit, the registration form pre-fills with your Google details — skip to Step 4 below.
4
Fill in Personal & Professional Details. Enter your full name, email address, specialisation, department, hospital/organisation, and medical registration number. These fields populate your digital signature on all reports.
5
Select Role: Physician / MD. In the Role section, choose Physician / MD. This grants full Tier 1 + 2 + 3 report access plus unrestricted EEG upload and SLDA analysis.
6
Apply your voucher (see §2). Enter NEURO2026 in the Voucher field before choosing a plan. The discount applies automatically.
7
Set username & password. Choose a username and a strong password (min. 8 characters). Confirm it in the second field.
8
Click "Create Account". Your account is created and synced to the NeuroSync PostgreSQL backend. The portal loads automatically and you land on the Overview Dashboard.

Returning Users — Login

1
Enter email & password → "Sign In →", or tap Continue with Google to authenticate with your linked Google account instantly.
2
Accept the HIPAA / DPDP consent banner. A data-handling notice appears once per session. Read it and click Accept & Continue.
3
Portal loads — your role badge appears top-right. A teal MD badge confirms Physician access. Sessions auto-expire after 8 hours of inactivity.
Cross-device access

To use your account on another computer, go to Profile tab → click Export Account. Save the .json file. On the new device, visit the portal, open the login screen, and click Import Account to upload the file.

Chapter 2 · 100% discount on first month — Professional plan

Applying the NEURO2026 Voucher

Voucher code

Your activation code is NEURO2026 — this gives 100% off your first month on the Starter or Professional plan.

How to Apply

1
During registration, scroll to the "Subscription Plan" section. Choose either Starter or Professional plan. For full MD/Physician access including Tier 3 reports, select Professional.
2
Scroll down to the "Voucher / Promo Code" field. Type NEURO2026 (case-insensitive) in the coupon input box.
3
Click "Apply". A green confirmation message appears: ✓ NEURO2026 applied — 100% off first month.
4
Complete registration normally. The discount is locked in.

Other Available Vouchers

CodeDiscountValid ForExpiry
NEURO2026100% off first monthStarter / Professional31 Dec 2026
MITADT5050% offStarter / Professional31 Dec 2026
WELCOME500₹500 flat offAny paid plan31 Dec 2026
NRDC2026100% off ProfessionalNRDC/CDSCO demo30 Jun 2026
IS360DEMO2 free uploads + reportsFree trial31 Dec 2026
Chapter 3 · Profile data appears in every report signature footer

Creating an MD / Physician Profile

Your Profile data populates the Reporting Clinician signature on every generated report and is stored encrypted in AWS PostgreSQL. It is critical for SaMD-grade traceability.

Fields to Complete

FieldWhat to EnterUsed In
Full NameDr. / Mr. / Ms. + full nameReport signature, session info
Specialisatione.g., Neonatal NeurologyReport footer
Departmente.g., NICU · PaediatricsReport footer
Registration No.MCI / State Board reg. numberSaMD audit trail
Organisation / HospitalFull hospital/clinic nameReport "Reviewing Clinician"
Mobile / WhatsApp+91 XXXXX XXXXXInternal use only
Address / City / PINClinical addressInternal use only

Saving Your Profile

1
Fill all required fields. All fields except Mobile are optional but completing them ensures legally valid report footers.
2
Click "💾 Save Profile → PostgreSQL". Your data syncs to the NeuroSync PostgreSQL backend. A green confirmation message appears at the right of the button.
Role badge

Your current role is shown in the top-right of every screen as a coloured badge. For Physician access it reads MD. If your badge shows a different role, contact your administrator to update it via the Sub-Account Manager in the Profile tab.

Changing Password

In the Profile tab, scroll to Change Password. Enter your current password, new password, and confirm. Click Update Password. Minimum 8 characters required.

Chapter 4 · EDF Upload tab — supports EDF · BDF · PDF · CSV · MAT

Uploading EEG Files

Supported File Formats

FormatExtensionSourceNotes
EDF / EDF+.edf / .edf+Any EEG systemPreferred — full 19-channel raw signal
BDF.bdfBioSemi24-bit biosemi format supported
PDF Report.pdfNihon Kohden, Natus, Cadwell, MEDILOG, NeurofaxEEG report PDF — timeseries rendered via PDF.js
CSV.csvEEGLAB, BrainVision exportComma/tab/semicolon separated, header auto-detected
MATLAB.matMATLAB v5 / EEGLAB .setSignal matrix extracted from byte offset 128

Maximum file size: 100 MB. Files larger than 100 MB will be rejected with an error.

Uploading a File

1
Click the "EDF Upload" tab. The upload workspace opens with a large drop zone, a subject bar, and a file history panel.
2
Drag and drop your file onto the drop zone — or click to browse. The drop zone accepts any supported format.
3
Confirm file staging. The file name, size, and detected type appear in the drop zone. A progress bar shows: Parsing… → SLDA Running… → Complete.
4
Verify the Subject Bar (top of screen). After parsing, the subject bar updates with patient name, ID, date, recording parameters, and clinician name.
5
Click "▶ Run SLDA Analysis". The SLDA engine runs 8 sequential steps: signal extraction → band power → delta/theta ratio → asymmetry index → PAZ ambiguity → KSI → classification → IRT seeding.
6
Auto-redirect to Overview. 600 ms after SLDA completes, the portal automatically switches to the Overview tab.
File history

Every uploaded file is saved in the session's File History panel. Up to 10 files are kept in active memory; older files auto-archive (up to 50).

Loading the Demo Dataset

Click Load Demo EDF (or the Demo PDF button) to instantly populate all views with a synthetic, illustrative EEG dataset — no file upload required, no real patient data involved. This is ideal for exploring all features before uploading patient data.

Chapter 5 · The command centre — all key metrics in one view

Overview Dashboard

The Overview (Dashboard) tab is the first screen after login and the automatic destination after SLDA analysis. It consolidates all critical EEG findings into a single scrollable command panel.

Metric Cards (top row)

Signal Quality %, Primary Finding, Classification (ERP/P300 · Resting · Motor Imagery · Epilepsy Screen), PAZ ambiguity zone %, KSI (kernel stability index), and NPSP Band designation.

BCI Confidence Bars

4-class posterior probability bars showing how strongly the SLDA engine associates the EEG with each of the four discriminant classes: ERP/P300, Resting State, Motor Imagery, Epilepsy Screen.

EEG Band Power Grid

Delta / Theta / Alpha / Beta / Gamma power values (µV²), δ/θ, α/β, θ/α ratios — all compared against reference ranges with NORMAL / MONITOR / HIGH status.

Asymmetry Index

Right/Left hemispheric delta asymmetry percentage. Values ≥30% flag high asymmetry (red), 15–29% moderate (amber), <15% normal (green). The dominant hemisphere and dominant electrode pair are named.

Report Access Cards

Three RBAC-gated cards — Tier 1 (all roles), Tier 2 (MD/PT/LAB), Tier 3 (MD/SA only). Unlocked tiers show "Open Report →"; locked tiers are greyed out.

Live Audit Chain

Bottom-right corner overlay showing the 4-step SHA-256 provenance chain: EEG Upload → Algorithm → Clinician → Report Sealed. Click "Verify → neurosync-erp.com" to validate tamper-evidence.

Chapter 6 · Real anatomical MRI with EEG/SLDA canvas overlays · 5 anatomical views

Anatomy MRI — Brain Views

Click Brain Views in the navigation. This tab renders 5 real brain MRI images with dynamic canvas overlays drawn from your SLDA analysis data.

ViewPlaneKey Annotations
Axial · Top SliceSuperior (z=113mm)Asymmetry excess zone, all 19 electrode positions, longitudinal fissure, L/R labels
Sagittal · MidlineMedial (x=130mm)NAS fiducial, Corpus Callosum, Thalamus, Brainstem
Coronal · Front SectionFrontal (y=142mm)Hemisphere excess zone, Hippocampus markers, Thalamus, fiducials
Lateral · Side ViewFull hemisphere4 lobe zones (Frontal, Parietal, Temporal, Occipital), lobe labels
Superior · Top Surface10-20 projectionAll 19 electrodes, CZ fiducial, heatmap legend note

Toggle Annotations

The annotation legend bar includes a Hide Annotations button. Clicking it removes all canvas overlays and shows the clean MRI images — useful for printing or clinical review of anatomy.

3D labelled brain grid

Below the 5 annotated real-MRI panels is a 3D Labelled Views Grid showing rendered 3D brain images with anatomical region labels: Sagittal, Axial, Coronal, Lateral, Superior, and EEG Source Regions.

Chapter 7 · Real anatomical brain base · electrode placement · delta power heatmap views

10-20 Montage & Channel Heatmap Views

Click 10-20 Montage in the navigation. This tab renders two side-by-side canvases on a real superior brain image background.

Left Panel — Electrode Montage

1
Brain background — a real anatomical MRI superior view, cropped and centred within an elliptical scalp outline.
2
19 electrode positions. Standard channels appear as teal/blue circles; excess channels appear as red/orange circles with a glow ring; moderate channels in amber.
3
Wire connections follow the standard 10-20 layout. A dashed yellow line marks the longitudinal midline.
4
Delta power % labels below each electrode circle.
5
ANTERIOR/POSTERIOR and L/R orientation markers.

Right Panel — Channel Delta Power Heatmap

A Gaussian radial heatmap over the same anatomical background — high values produce large red-orange blobs, low values small blue-teal blobs, blending to a smooth power topography. A colour scale bar runs from "Low Δ" (deep blue) to "High Δ" (deep red).

Channel-by-Channel Delta Power Bar Chart

Below both canvases, a full-width horizontal bar chart shows all 19 electrodes ranked by delta power.

Chapter 8 · Stepped Linear Discriminant Analysis · Prediction Ambiguity Zone

SLDA / PAZ Analysis Engine

Click SLDA / PAZ in the navigation. This tab visualises the mathematical internals of the classification engine.

PAZ 2D Scatter Plot

A 2D projection of SLDA discriminant space (L₀₁ × L₀₂ axes). Shows the ERP/P300 class ellipse, the alternate-class ellipse, the Motor Imagery cluster, and the PAZ boundary (red dashed, ε=0.15). The active subject's data point is plotted as a green/amber/red dot depending on PAZ score.

PAZ Ambiguity Dial

A semi-circular gauge (0%–100%) showing PAZ Ratio, number of ambiguous samples, KSI value, and discriminant distances. Green zone = STABLE (<5%), amber = MONITOR (5–20%), red = HIGH (>20%).

PAZ 3D Ellipsoid

A wide SVG showing both class ellipsoids in ±2σ covariance space. The PAZ boundary line divides the space; the subject's position and axis labels are shown.

EEG Timeseries (19 channels)

A 10-second synthetic raster of all 19 channels, with the dominant channels highlighted.

Brain Lobe Activation (SLDA)

A schematic SVG of the brain in lateral profile with animated pulsing zones for each lobe, encoding activation level from SLDA class weighting.

EEG Epoch View (19-ch raster)

Compressed raster across 40 1-second epochs for all 19 channels — visually shows temporal consistency of the asymmetry.

Chapter 9 · Structured Therapeutic Engagement Matrix · Full scoring from Band B onwards

STEM Domains — Cognitive Scoring

Click STEM in the navigation. STEM (Structured Therapeutic Engagement Matrix) maps EEG findings to 8 cognitive-developmental domains for intervention planning.

DomainBasis
S1 — Auditory ProcessingERP/P300 amplitude and latency mapping to auditory cortex activation (T3/T4 zone)
S2 — Visual-SpatialO1/O2 occipital power and alpha emergence indicating visual cortex readiness
S3 — SensorimotorC3/C4 central delta/beta ratio linked to motor cortex development and lateralisation
S4 — Language / CommunicationF3/F7 left frontal and T3 temporal coherence markers for language pathway readiness
S5 — Social-EmotionalFp1/Fp2 frontal asymmetry relative to social engagement and affect regulation
S6 — Cognitive IntegrationFz/Cz fronto-central coherence and theta/alpha transition indicating working memory scaffolding
S7 — Executive FunctionF4/Fz right frontal dominance and beta band emergence correlating with planning and inhibition
S8 — Adaptive / MotorP3/P4 parietal and C3/C4 central band pattern for fine/gross motor adaptation readiness
Availability note

Full STEM scoring activates from NPSP Band B (18 months+). For neonatal subjects (Band A, 0–18 months), STEM shows preliminary flags only — a banner confirms "Full STEM scoring begins at Band B."

Chapter 10 · Neuro-Paediatric Screening Protocol · Bands A–E · Full lifespan

NPSP Protocol — Age-Band Assignment

Click NPSP in the navigation. The NPSP Protocol defines 5 age-normalised EEG recording and analysis bands from birth through adulthood.

BandAge RangeRecording Type
Band A0–18 months (Neonatal)Passive ERP · No active task
Band B18 months–5 years (Toddler)Passive + simple stimuli · Object permanence
Band C5–12 years (Paediatric)Active task ERP · N2/P3 paradigms
Band D12–18 years (Adolescent)Cognitive load · Go/No-Go · Flanker
Band E18+ years (Adult–Geriatric)Full adult protocol

The active band row is highlighted in teal and carries a "▶ ACTIVE — Current Subject" indicator. The NPSP table also lists stimuli protocols, ERP targets (P300, N2, N400, etc.), and the relevant STEM domains for each band.

Chapter 11 · Intervention Response Targeting · EEG-guided therapy recommendation

IRT Intervention — Priority Matrix

Click IRT in the navigation. The portal tab shows a preview IRT table; the full IRT report is in Tier 3 (MD/SA only).

IRT Preview Table (All Roles)

PriorityColourMeaning
HIGHRedRequires immediate intervention — elevated delta excess ≥30% asymmetry
MODERATEAmberScheduled therapy recommended — asymmetry 15–29%
MONITORBlueWatch and reassess at next EEG — asymmetry <15% or PAZ <5%

IRT Zones Covered

Right Fronto-Central, Left Fronto-Central, Temporal Lobe, Occipital/Visual, Frontal Executive, Parietal Sensory, and Global/Multi-zone entries. Each zone links to specific physiotherapy, occupational therapy, home programme, and specialist referral actions.

Full IRT report

Click → View Full IRT Report (Report Tier 3) at the bottom of the IRT tab to navigate directly to the Tier 3 clinical report, which includes a full 5-view MRI reference, personalised therapy schedule, home programme, referral roadmap, and requires physiotherapist co-sign.

Chapter 12 · A4 print-ready reports · RBAC gated · SHA-256 audit chain

Report Generation: Tier 1 / Tier 2 / Tier 3

Tier 1 — Generic Clinical Summary (all roles · 3 A4 pages)

  • 5 annotated real MRI views + canvas overlays
  • EEG band power table
  • Key clinical findings flags (HIGH/MOD/OK)
  • Brain lobe activation map
  • 19-channel EEG epoch raster view
  • Parent/caregiver plain-language summary
  • Full SHA-256 audit chain on every page

Tier 2 — Analysis + Prediction (MD / PT / LAB / SA · 3 A4 pages)

  • 5-view 3D labelled brain grid
  • Full SLDA/PAZ scatter + 3D ellipsoid
  • Cognitive prediction confidence matrix
  • STEM domain scores (S1–S8)
  • NPSP band assignment + stimuli protocol
  • SaMD validation metrics

Tier 3 — Full IRT Intervention Plan (MD / SA only · 1 A4 page)

  • Full 5-view annotated MRI (IRT targeting)
  • Priority intervention matrix (all zones)
  • Daily home programme schedule
  • Physiotherapist co-sign block (mandatory)
  • Tamper-evident SHA-256 chain block
SaMD disclaimer — required on all reports

Every report page includes: "RESEARCH ANALYSIS ONLY — NOT A STANDALONE MEDICAL DIAGNOSIS. All findings must be clinically correlated by a qualified neurologist or neonatologist before any clinical action is taken." This is mandated under NeuroSync ERP's CDSCO Test License terms and SaMD Class B guidelines.

Chapter 13 · Browser print → Save as PDF · A4 portrait · No app required

Downloading & Printing Reports as PDF

Method 1 — Print Button (Recommended)

1
With the desired tier displayed, click "🖨 Print PDF" in the tier bar.
2
In the print dialog, set Destination to "Save as PDF".
3
Set paper to A4, orientation Portrait, margins None.
4
Click Save / Print. Navigation bars and overlays are automatically hidden by the print CSS.

Method 2 — Print All Tiers Together

In the tier bar, click "All Tiers (Print)" to display all accessible tiers in sequence, then use the Print PDF button.

Method 3 — Keyboard Shortcut

While on the Reports tab, press Ctrl+P (Windows/Linux) or ⌘+P (Mac).

File naming convention

NeuroSync ERP™ automatically sets the print document title to NS_[PatientID]_T[Tier]_[Date] before the print dialog opens.

Chapter 14 · NEW · Open-dataset validation and benchmarking

PhysioNet Validation

Access

The PhysioNet Validation tab is restricted to Neurologist / Researcher / Admin / SA roles — it does not appear for Physician/MD or Caregiver/Guest accounts. This reflects its purpose: benchmarking the SLDA/PAZ engine against open, de-identified research datasets, not analysing individual patients.

Click PhysioNet Validation in the navigation (under Research Toolkit). This tab runs and displays benchmark comparisons of the analysis engine against established open EEG corpora.

Benchmark Metrics Displayed

MetricWhat It Measures
Sensitivity / SpecificityClassification accuracy against labelled reference epochs
AUC-ROCDiscriminative performance across the operating range
AccuracyOverall correct-classification rate on the benchmark cohort
ICC (test-retest)Reproducibility of the measurement across repeated runs
Brain Age MAEMean absolute error of any age-prediction component, where applicable
Research use only

PhysioNet Validation results describe engine performance on open research datasets. They are not, and must not be interpreted as, a clinical validation of any individual patient's report. This tab is separated from patient-facing tiers precisely to keep that distinction clear.

Chapter 15 · NEW · Intraoperative baseline-vs-current change detection

SSEP Telemetry Monitoring

The SSEP Monitor tab (under Telemetry Monitoring) supports somatosensory evoked potential (SSEP) monitoring during surgery, comparing a patient's current readings against their own earlier baseline — a relative, change-detection function, distinct from the diagnostic SLDA/PAZ engine described in §8.

How It Works

1
A baseline SSEP reading is captured (typically pre-incision) and stored for the case.
2
Subsequent readings during the case are compared automatically against that same baseline.
3
A channel is flagged when amplitude drops ≥50% or latency increases ≥10% from the patient's own baseline — the standard IONM alarm convention.
4
Flagged channels display in the Channel Detail table with the real percentage change; unflagged channels stay quiet.

Reading the Status Banner

StatusMeaning
STABLENo channel currently exceeds alarm criteria
MONITORA change was detected on a channel whose baseline or current reading was not independently reliable — flagged for awareness, not a confident alert
HIGHA channel independently confirmed reliable on both readings has crossed the alarm threshold
Informs, does not drive

Monitoring support only. Relative trend comparison to the patient's own pre-induction baseline. Not a diagnostic or prognostic output. Clinical decisions must be made by the responsible surgical/neuromonitoring team.

Deployment status

SSEP Telemetry Monitoring uses a separate regulatory track from the SLDA/PAZ engine's existing CDSCO Test License — it is not automatically covered by that license and is evaluated independently. Feature availability may vary by account tier and rollout phase.

Chapter 16 · RBAC matrix · SaMD compliance · HIPAA · DPDP Act 2023

Role Access Reference & Compliance

RBAC — Role Based Access Control

RoleBadgeTier 1Tier 2Tier 3SLDAUpload
Physician / MDMD✅✅✅✅✅
System AdministratorSA✅✅✅✅✅
PhysiotherapistPT✅✅🔒✅✅
Researcher / LabLAB✅✅🔒✅✅
AdministratorADMIN✅✅✅✅✅
Caregiver / GuestCG/GUEST✅🔒🔒Limited✅
Verify before relying on this table

This table describes intended access policy. It has not yet been independently confirmed against every gating check in the live application for every role — in particular, Physiotherapist Tier 3 restriction and Administrator's full-tier access should be verified against the actual report-generation code before being treated as guaranteed behaviour.

Compliance & Data Protection

Data Encryption

All PHI and EEG data encrypted at rest (AES-256) and in transit (TLS 1.3). Stored in AWS ap-south-1 (Mumbai) within India's data residency requirements, on a PostgreSQL backend.

HIPAA Compliance

Protected Health Information (PHI) handled per HIPAA Security Rule. Minimum necessary access principle applied through RBAC.

DPDP Act 2023

India's Digital Personal Data Protection Act 2023 compliance. Data deletion requests to dpo@is360tech.com. No cross-border transfer without consent.

CDSCO / ICMR SaMD

NeuroSync ERP™ holds a CDSCO Test License, granted for live clinical evaluation, and is a Software as a Medical Device (SaMD) Class B regulated under CDSCO and ICMR guidelines. All AI outputs require physician clinical correlation.

SHA-256 Audit Chain

Every analysis and report event is recorded in a 4-step tamper-evident blockchain-style chain: EEG Upload → Algorithm → Clinician Confirm → Report Sealed. Verifiable at neurosync-erp.com/verify.

Session Security

Sessions auto-expire after 8 hours of inactivity. All session tokens stored only in localStorage. Logout clears all session data immediately.

Quick reference — keyboard shortcuts

Ctrl/⌘+P — Print/save active report as PDF | Esc — Close modal/dialog | Tab navigation is fully accessible via keyboard.

Support

Technical issues: support@is360tech.com
Data / Privacy: dpo@is360tech.com
Clinical queries: clinical@neurosync-erp.com
Portal: neurosync-erp.com

NeuroSync ERP™ v4.2 — User Instructions Manual · NS-UM-2026-v4.2 · © 2026 IS360 Technologies & Services Pvt. Ltd. · CDSCO Test License Granted · SaMD Class B · CDSCO · HIPAA · DPDP Act 2023 · All rights reserved